SERUMS
APSTEM (STEM CELL BUILDER)
PROMOTES THE REPRODUCTION OF FACIAL CELLS
Hydrophilic apple stem cell serum
TRADITIONAL CHINESE MEDICINE ACTIONS
Tonifies facial qi
BIOMEDICAL ACTIONS
Promotes the reproduction of skin cells under the epidermis
HOW IT WORKS
Skin ages in more than one manner. One of the most destructive processes in the skin is the slowing of the epidermal cell renewal process. The process slows over time, and, therefore, our skin begins to amass more dying cells than new ones. This allows us to begin to develop sagging skin, wrinkles, and lines. It is also part of the damage that occurs because of exposure to UV rays.
PRODUCT INFORMATION
Apple stem cells of the famous Uttwiller Spatlauber trees of Switzerland are scientifically proven to activate the epidermal cells of the skin to start self-renewing at a rate similar to that of youth. This action thwarts the skin from developing lines and wrinkles, sagging, and appearing unhealthy or dull.
APSTEM offers the benefits of lab-grade stem cells, as opposed to wholesale products.
Our stem cells are natural, pure, and without preservatives. They are among the most potent extracts of the sought-after apple stem cells, and have been combined with other effective and natural compounds to create optimum results.
Our experts have formulated a daily-use serum that includes the natural ingredient PhytoCellTec, an extract of the Uttwiller Spatlauber fruit. They have also added several other skin-boosting compounds—chemical free and natural—to our serum, including fatty acids and rosehip seed oil high in antioxidants such as vitamins A and E. We also include 100% pure hyaluronic acid (HLA) to allow the skin to hold onto high amounts of moisture (about 1,000 ml per gram of HLA); and lecithin with linoleic acid and other vitamins for the skin.
Information provided by AcuMicro
COLLAGEN XG+®
BUILDS COLLAGEN AND ELASTIN
Hydrophilic xiang gu serum (Lentinus Edodes Extract or Shiitake Mushroom extract)
TRADITIONAL CHINESE Medical ACTIONS
Strengthens facial qi
Expels wind
Tonifies dry, deficient skin
BIOMEDICAL ACTIONS
Naturally builds collagen and elastin
BIOMEDICAL INFORMATION
CollagenXG+® contains a shiitake mushroom extract that thwarts collagen deterioration and improves the organization, quality, and structure of collagen, all of which are linked to a firmer and smoother complexion
The amount of collagen in our skin decreases, as we age, and enzymes such as matrix metalloproteinases (MMP) increase. This leads to signs of aging, such as a reduction in firmness or roughness. Collagen acts as a strong antioxidant that lessens damage by reactive oxygen species (ROS) as well as lipid peroxidation. It assists with type I collagen synthesis and increases PLOD1 levels, which adds to protein quality while reducing carbamylation.
It also reduces the degradation of collagen by MMPs and glycation, the bonding of sugar molecules to proteins.
RESEARCH STUDIES
19 female volunteers (41–55 years old) applied CollagenXG+® twice daily for 56 days
Volunteers reported improvement of firmness and a reduction of neck folds, along with a smoother appearance of the décolleté, neck, and face, and a decrease in the appearance of roughness. Also noted was an improvement in skin recovery after distension, a quality associated with younger skin, which means the skin bounces back quickly
In vitro research has shown that synthesis of type I collagen increased by 36.5% with 1% Collagen+ An increase of 21.9% PLOD1 with 3% CollagenXG+®
2% CollagenXG+® reduced carbamylation by 75.9%, which could lead to less deterioration and improved organization of collagen
KEY BENEFITS
Encourages firmer appearance of neck, face, and décolleté
Increases the synthesis of collagen
Decreases the deterioration of collagen
Improves the quality of collagen
Prevents the degradation of matrix proteins, such as collagen and elastin
Acts as an anti-oxidant
Information provided by AcuMicro
ELASTIN FL+®
TREATS ACNE PRONE GREASY SKIN AND THINNING SKIN
Hydrophilic fu ling serum (Poria Cocos)
TRADITIONAL CHINESE Medical ACTIONS
Treats dampness due to spleen & kidney qi deficiency
BIOMEDICAL ACTIONS
Natural collagen & elastin builder
Best for damp, acne-prone, greasy skin & older, thinning skin
BIOMEDICAL INFORMATION
Fu Ling is a celebrated herb in traditional medicine in Asia, where it is used as an antioxidant, purifying agent, and softening agent. The part used in Elastin FL+® is the sclerocia (mycelium), which is rich in triterpenes and polysacchrides (pachyman).
Elastin FL+® promotes skin thickness, microcirculation, and radiance.
Lessens the appearance of wrinkles characteristic of aging.
Good during menopause and for mature skin.
Mature FL intensifies the expression of the CDRR trans-membrane glycoprotein receptor, thus improving hyaluronic acid binding to the dermis and epidermis.
SPRR is a family of small proteins located in the dense envelope of the epidermis. Because of aging and menopause, these proteins become overexpressed, which leads to important skin imbalances. Elastin FL+® diminishes the expression of SPRR and improves the appearance of mature skin.
Information provided by AcuMicro
LUMOS BRIGHTEN®
REMOVES BRIGHT SPOTS AND MELASMA
Hydrophilic zao lei serum (formulated algae from the coast of Spain)
TRADITIONAL CHINESE MEDICINE ACTIONS
Moves qi and blood
BIOMEDICAL ACTIONS
Clears melanin pigmentation from the skin
Gets Rid Of Age Spots and Melasma
BIOMEDICAL INFORMATION
Acts on melanin deposition and production processes in the skin to improve luminosity and decrease visibility of hyperpigmented areas to balance out the skin tone
It has reduced melan-A protein levels (40%), thus interfering with development of melanosomes
It reduces the amount of human tyrosinase protein by up to 48.9%, and its activity by 24.3%
Decreases the amount of melanin pigment produced by melanocyte in culture by 61.3%
acting on melanocytes resulted in a 69% lower uptake of particles (phagocytosis)
Neutralizes hyperpigmentation, which is related to age spots, in reconstituted epidermis
It regulates gene expression of melanogenic signaling proteins to reduce the formation and maturation of melanosomes, reduces tyrosinase levels and activity, and reduces melanin update by keratinocytes. Further, it induces the expression of genes involved in DMA repair, which is necessary due to the loss of UV-protective pigment
Lab tested for specific concentration and quality control
HUMAN STUDY
22 female volunteers of Asian descent (38–53 years old) with hyperpigmented regions of their skin applied a cream with 2% Lumos® or a placebo cream twice a day for 8 weeks
Treatment increased luminance (L*) (2.5%) and inpidual topological angle (ITA) (15.3%), and decreased contrast of dark spots by 12.7%, leading to a great improvement in evenness
The treatment shrank the area of dark spots (6.9%) and decreased their melanin content by 61.1%
Information provided by AcuMicro
OCCULUS™
REMOVES UNDER-EYE BAGS
Hydrophilic hai zao serum (seaweed from the coast of Spain)
TRADITIONAL CHINESE MEDICINE ACTIONS
Moves blood and interstitial fluid
Resolve damp fluid retention
BIOMEDICAL ACTIONS
It helps clear bilirubin and fluid buildup around the eyes
Gets rid of eye bags, dark circles, & puffiness
BIOMEDICAL INFORMATION
Liquid retention because of higher permeability of blood vessels causes eye puffiness to appear. When added to bilirubin accumulation from hemoglobin breakdown, induces vascular pigmentation and, therefore, dark circles. Further, deterioration of skin support proteins, such as collagen and elastin, contributes to heightened visibility of such signs, in addition to wrinkle development
Occulus™ decreases vascular permeability to ameliorate eye bags and dark circles
Stimulates bilirubin degradation to reduce vascular pigmentation that leads to dark coloration under the eyes
Stimulates production of elastin and type I collagen by dermal fibroblasts
Reduces glycation of collagen to sustain elasticity and strength of the dermis
In vivo, it improves the appearance of all signs of aging in the eye contour area, including puffiness, wrinkles, and dark circles
Occulus™ provides complete care of the eye contour area by lessening fluid extravasation and increasing the degradation of bilirubin. It also improves collagen and elastic synthesis and decreases the formation of advanced glycation end products (AGE) for a younger and brighter look. Isolated from a naturally occurring marine microorganism isolated in Playa Paraiso, Tenerife Island, Spain, it is produced by through biotechnology, so there is no extracting or harvesting from nature
The look of the eyes transmits attractiveness and beauty. It is essential in interpersonal communications. The delicate skin around the eyes becomes thinner as we age, and therefore it is more susceptible to age-related changes. Eye puffiness appears because of liquid retention, a consequence of the higher permeability of blood vessels. When that is added to bilirubin accumulation from hemoglobin breakdown, it induces vascular pigmentation and, therefore, dark circles. Further, the deterioration of skin support proteins, such as collagen and elastin, contributes to increased visibility of such signs, as well as the development of wrinkles.
RESEARCH STUDIES
A panel of 21 females (22–54 years old) with dark circles applied once a day for 28 days a placebo cream on one side of the eye contour area and a cream with Occulus™ on the other side, twice a day. The vascular component (red color) of dark circles was then calculated from high resolution photographs obtained under cross-polarized light.
The active ingredient reduced the vascular component of dark circles by 1.5% and had a 35.7% greater effect than the placebo.
A group of 20 females (aged 41-66), showing eye bags, used a cream with Occulus™ marine ingredient, twice a day for 28 days, on half the face around the eye and a placebo cream on the other half. Fringe projection technique was used to evaluate eyebags volume. The results were evident after 14 days, reducing them by 8.2% after 28 days.
A panel of 18 females (aged 40-54) applied a placebo cream or a cream with Occulus™ on crow’s feet wrinkles of one eye or the other, twice a day for 14 days. Measurement of in vivo skin topometry of crow’s feet was performed by fringe projections. Occulus™ provided a general smoothing effect by reducing roughness by 9%, mean wrinkle depth by 8.75%, and maximum wrinkle depth by 9.8%.
KEY BENEFITS
Reduces vascular permeability to ameliorate eye bags and dark circles
Enhances bilirubin degradation to reduce vascular pigmentation that causes dark coloration under the eyes
Promotes production of elastin and type I collagen by dermal fibroblasts
Lessens glycation of collagen to maintain strength and elasticity of the dermis
In vivo, it improves the appearance of all signs of aging in the eye contour area, including puffiness, wrinkles, and dark circles
Information provided by AcuMicro
REJUV®
PROMOTES REPAIR AND AFTERCARE HEALING
Hydrophilic ji xue cao serum (Asiatic Pennywort)
TRADITIONAL CHINESE MEDICINE ACTIONS
Clears heat
Resolves swelling
Removes toxicity
BIOMEDICAL ACTIONS
Helps speed up facial repair process post microneedling
BIOMEDICAL INFORMATION
Rejuv Xue Cao® is used to support faster healing of scratches, small wounds, and superficial burns, as well as as an anti-inflammatory for insect bites, minor itching, and eczema. It is traditionally used in the management of dermatological conditions in its area of origin.
Active ingredients are pentacyclic triterpenoids, which have activating and regulating functions. They act on the collagen present in many organs. Major components in skin are collagens type I and II. Aging in the skin is related principally to a decrease in type I collagen levels that also plays a principal role in wound healing. Research shows that the main constituents of Rejuv Xue Cao® – Asiatic acid, madecassic acid, and asiaticoside – increase collagen synthesis. Beyond stimulating the synthesis of collagen, it also improves the skin’s tensile strength.
Rejuv Xue Cao® is made using the finest grade Ji Xue Cao. Using a hydrophilic extraction technique, Rejuve Cao is able to penetrate deeply into the skin prior to or following a Microneedling session. This topical is best used to assist in speeding repair processes following a microneedling session.
Information provided by AcuMicro
SENESCENCE TMD
ENLIVENS SKIN CELLS
Hydrophilic tian men dong serum (formulated asparagus tuber)
TRADITIONAL CHINESE Medical ACTIONS
Boosts primal kidney qi essence of facial cells
BIOMEDICAL ACTIONS
It helps cells regain their ability to grow and divide
BIOMEDICAL INFORMATION
Extensive research has shown that Tian Men Dong substantially combats two principal signs of skin aging by providing the skin with a more firm and thicker appearance
Its unique mechanism of action helps reduce noticeable signs of the naturally occurring cellular process we know as senescence, therefore delaying the appearance of skin aging by decades
It helps stimulate the skin’s own autophagy capabilities, which slows the process of cellular senescence (in vitro immunofluorescent detection of LC3 protein, a key autophagic marker, in fibroblasts in monolayer culture)
About 340 physiochemical analyses are conducted each season to ensure that our Tian Man Dong from Navarra, northern Spain, remains among the most exquisite available and superior to nearly any other variety in the world. Tian Men Dong contains particularly high quantities of saponins, with Yamoscin and Dioscin, as major components. Saponins are positive modulators of autophagy.
RESEARCH STUDIES
In vivo greatly improves collagen density and dermis thickness
Ex vivo nearly completely protects donor skin against signs of sunburn caused by UV radiation exposure
BENEFITS
It heightens the skin’s innate strength to delay cellular aging by decades
Accelerates the skin’s detoxifying processes, independent of age
Delivers an overall skin rejuvenation effect
Raw material is approved by ECOCERT GREENLIFE and conforms to the ECOCERT Natural and Organic Cosmetics Standard
Information provided by AcuMicro